The Lacursome® manufacturing technology

The Lacursome® manufacturing technology, developed by Aliveda, protects, carries and improves the absorption of active principles. Lacursome is an acronym of LActoferrin-CURcumin- microSOMal and it allows the production of lipidic nanoparticles, which hold and carry the active principles. The nanoparticles are coated by fatty acids from the cocoa butter, they form a shell which holds […]

The importance of non-pharmacologic treatment of cystitis

Cystitis is an inflammation of the lower urinary tract, involving bladder and urethra. In many cases it is caused by a bacterial infection, but it can have a mycotic origin or be aseptic, which means not associated to microorganisms but to stresses, irritable chemical agents, drugs use, trauma. The bacterial cystitis is caused by bacteria […]

The role of melatonin in gastritis and gastro-esophageal reflux disease

Gastritis is a chronic or acute inflammation of the gastric mucosa. Acute gastritis is sudden inflammation, caused by imbalance in the mucosal mechanisms of defense, represented by the mucus layer and bicarbonate secretion, and gastric acidity, leading to gastric erosion. Chronic gastritis is a gradual inflammation, less aggressive, which lasts in time, generally caused by […]

Vitamins

Vitamins are micronutrients, needed in very low amount to satisfy the metabolic needs of the body. Some of them can be auto-produced, but most of them should be received from diet. Vitamins are involved in many reactions and metabolic processes and contribute to the development and correct operation of tissues and organs; moreover, some of […]

The role of probiotics in gut microbiota health

The gut microbiota Human microbiota is the aggregate of the symbiotic microorganisms living in the human body, without damaging it; the gut microbiota is the portion that colonize the intestine. The microbiota shapes itself with birth and since then it modifies itself with external factors, as the environment, diet, the use of drugs, etc. So, […]

The role of sirtuins in tendinopathy

Tendinopathies are a group of diseases causing pain or injury to tendons. At the basis of a tendinopathy there is a trauma or a functional overload of a suffering tendon: the mechanical stress triggers micro-traumatic events, which becomes pathologies when the traumatic events causing degeneration of the tissue predominate the regeneration processes. Sirtuins are histones […]

The role of group B vitamins in neuroprotection

The incidence of cognitive impairment and dementia increases with aging, so it is of much interest to identify and target the risk factors, with the aim of slowing or prevent the cognitive impairment age-related. Numerous studies correlate the group B vitamins shortage to phenomena involved in Alzheimer disease pathogenesis and other neurodegenerative diseases. In literature, […]

PEA and intestinal health

Palmitoylethanolamide (PEA) is an endogenous fatty acid amide, synthetized by immune and nervous cells and it is involved in chronic pain and inflammation signaling: endogenous PEA levels increase in response to external stresses, but in chronic condition they can be inadequate to maintain homeostasis, so there is the possibility to administer exogenous PEA, with analgesic […]

NMN and mild cognitive impairment: an innovative approach

Mild Cognitive Impairment (MCI) is the pre-clinical phase between healthy aging and dementia; it is characterized by mild alteration in the cognitive functions, which do not interfere with the daily life and usual activities. It is estimated that 19% of the over-65 is affected and 46% of these cases evolve in dementia in the following […]

Probiotics to treat Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) is a gastrointestinal disorder, not associated to structural or biochemical alteration, chronic, with abdominal pain, recurrent uneasiness, altered intestinal motility, with diarrhea, constipation and bloating as recurrent symptoms. IBS cases diarrhea if the intestinal motility is increased, causing a lower water absorption from the gut; meanwhile it causes constipation if the […]